Color Atlas of Histopathology of the Cervix Uteri

Color Atlas of Histopathology of the Cervix Uteri
Second Edition

Gisela Dallenbach-Hellweg
Magnus von Knebel Doeberitz
Marcus J.Trunk

The new edition of this atlas integrates all significant advances made in the past 15 years

in molecular pathology, tumor virology, and genetics of cervical cancer. It emphasizes

the importance of these advances in facilitating its pathological diagnosis and in opti-

mizing clinical management and prognosis. A new chapter on immunohistochemistry

has been added, which includes refined detection methods, e.g., the overexpression of

p16INK4a as a molecular marker in the early differential diagnosis of premalignant le-

sions. The section on etiology and pathogenesis in human papillomavirus-induced

neoplasia has been incorporated to represent new insights into the sequences of cellu-

lar and nuclear deregulation at the molecular level.All chapters have been revised to in-

clude the newest advances and relevant experiences in how to interpret and manage

cervical disease; they are supported by the addition of 35 new microphotographic illus-

trations. The tumor nomenclature is adapted to the latest edition of the WHO classifi-

cation; the morphology code of the international classification of diseases for oncology

(ICD-O) has been added. We have also updated the list of references by adding recent

relevant publications.Again, the staff of Springer-Verlag deserve our thanks for their patience and skill in preparing the manuscript and in reproducing the microphotographs.

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